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New treatment begins to help people breathe better as North East Trust becomes first to use drug

Patients at South Tyneside and Sunderland NHS Foundation Trust (STSFT) are the first in the region to benefit from a drug which replaces the need for surgery to help them breathe better. It is also one of a handful in the country which is now using Dupilumab to help those with nasal polyps.These are painless […]

Patients at South Tyneside and Sunderland NHS Foundation Trust (STSFT) are the first in the region to benefit from a drug which replaces the need for surgery to help them breathe better.

It is also one of a handful in the country which is now using Dupilumab to help those with nasal polyps.
These are painless soft growths inside the nose. They are not usually serious, but they can keep growing back and block the nose if not treated.

Symptoms can include a blocked or runny nose, a feeling that mucus is slowly dripping down the back of the throat which is known as postnasal drip, a reduced sense of smell or taste and snoring.

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammation of the nasal passages and sinus cavities. It affects 6% of the adult population. It leads to around 40,000 operations in England and Wales and 75,000 outpatient visits a year.

Dupilumab works by blocking specific proteins in the immune system that cause swelling and tissue irritation in your nose and sinuses.

Tom Bradish is a consultant who works in the Trust’s Ear, Nose and Throat (ENT) Team and has carried out the treatment.

It is given through an injection in the tummy or thigh every two weeks.

He said: “We are using Dupilumab to help our patients who have a condition called severe chronic sinusitis with nasal polyps. This can cause them a lot of discomfort and they often need to have surgery many times during their life.

“This drug works by blocking signals which cause inflammation. It means they see a big reduction in their symptoms and the need for surgery.

“This treatment has come about thanks to a team effort. Members of our pharmacy, medical team, nurses and managers have pulled all the stops.

“All this hard work means we now have a way to help treat these patients in a new way, without the need for surgery. It is a great success that we became the first in the UK to start a patient on this treatment.”

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